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His sexual impotence turned him into a horrible monster!
A doctor—on orders from a sentient brain—kidnaps intimate couples and takes them to his mansion as prisoners. He injects his subjects with a substance to 'enhance' their sexual abilities. The curious doctor then forces his hostages to have sex. While they are making love, he drains a fluid from them, which he needs to prevent himself from transforming into a monster.

Needlestick

The Brain-Stealers

Frontier(s)

Dr. Goldfoot and the Bikini Machine

Back to the Future

Bride of Frankenstein

Back to the Future Part III

Nutty Professor II: The Klumps

The Devil Commands

Zombie Death House

Pandemonium

Return of the Ape Man